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The headache had slowly made its presence known, occupying one synapse at a time until it was impossible to ignore. She swallowed 600 milligrams of ibuprofen with a full glass of water, and then chased it with a cup of coffee. By the afternoon, she had repeated this routine four times. When her vision blurred, she called her doctor, who requested that she come into his office. By the time she grabbed her purse to leave, she had gone blind.